Publications

Publications in TUHAT database

 

Publications in 2015

Burke Ó, Benton S, Szafranski P, von Dadelszen P, Buhimschi SC, Cetin I, Chappell L, Figueras F, Galindo A, Herraiz I, Holzman C, Hubel C, Knudsen U, Kronborg C, Laivuori H, Lapaire O, McElrath T, Moertl M, Myers J, Ness RB, Oliveira L, Olson G, Poston L, Ris-Stalpers C, Roberts JM, Schalekamp-Timmermans S, Schlembach D, Steegers E, Stepan H, Tsatsaris V, van der Post JA, Verlohren S, Villa PM, Williams D, Zeisler H, Redman CW, Staff AC; Global Pregnancy Collaboration. Extending the scope of pooled analyses of individual patient biomarker data from heterogeneous laboratory platforms and cohorts using merging algorithms. Pregnancy Hypertens. 2016 Jan;6(1):53-9. DOI:10.1016/j.preghy.2015.12.002

Raikkonen, K., Pesonen, A. -K., O’Reilly, J. R., Tuovinen, S., Lahti, M., Kajantie, E., … Reynolds, R. M. (2015).  Maternal depressive symptoms during pregnancy, placental expression of genes regulating glucocorticoid and serotonin function and infant regulatory behaviors. Psychological Medicine, 45(15), 3217-3226. DOI: 10.1017/S003329171500121X

Grauers, A., Wang, J., Einarsdottir, E., Simony, A., Danielsson, A., Akesson, K., … Gerdhem, P. (2015). Candidate gene analysis and exome sequencing confirm LBX1 as a susceptibility gene for idiopathic scoliosis. The spine journal : official journal of the North American Spine Society, 15(10), 2239-2246. DOI: http://dx.doi.org/10.1016/j.spinee.2015.05.013

Kaartokallio, T., Cervera, A., Kyllonen, A., Laivuori, K., Kere, J., Laivuori, H., & FINNPEC Core Invest Grp (2015). Gene expression profiling of pre-eclamptic placentae by RNA sequencing. Scientific Reports, 5, [14107]. DOI: http://dx.doi.org/10.1038/srep14107

Koivusalo, S. B., Rönö, K., Klemetti, M. M., Roine, R. P. A., Lindström, J., Erkkola, M., … Stach_Lempinen, B. (2015). Gestational Diabetes Mellitus Can Be Prevented by Lifestyle Intervention: The Finnish Gestational Diabetes Prevention Study (RADIEL): A Randomized Controlled Trial. Diabetes Care. DOI: http://dx.doi.org/10.2337/dc15-0511

van Uitert, M., Moerland, P. D., Enquobahrie, D. A., Laivuori, H., van der Post, J. A. M., Ris-Stalpers, C., & Afink, G. B. (2015). Meta-Analysis of Placental Transcriptome Data Identifies a Novel Molecular Pathway Related to Preeclampsia. PLoS One, 10(7), [0132468]. DOI: http://dx.doi.org/10.1371/journal.pone.0132468

Reynolds, R. M., Pesonen, A. -K., O’Reilly, J. R., Tuovinen, S., Lahti, M., Kajantie, E., … Raikkonen, K. (2015). Maternal depressive symptoms throughout pregnancy are associated with increased placental glucocorticoid sensitivity. Psychological Medicine, 45(10), 2023-2030. DOI: http://dx.doi.org/10.1017/S003329171400316X

Klemetti, M. M., Laivuori, H., Tikkanen, M., Nuutila, M., Hiilesmaa, V., & Teramo, K. (2015). Obstetric and perinatal outcome in type 1 diabetes patients with diabetic nephropathy during 1988-2011. Diabetologia, 58(4), 678-686. DOI: http://dx.doi.org/10.1007/s00125-014-3488-1

Lokki, A. I., Aalto-Viljakainen, T., Meri, S., & Laivuori, H. (2015). Genetic Analysis of Membrane Cofactor Protein (CD46) of the Complement System in Women with and without Preeclamptic Pregnancies. PLoS One, 10(2), [0117840]. DOI: http://dx.doi.org/10.1371/journal.pone.0117840

Murtoniemi, K., Villa, P. M., & Laivuori, H. (2015). Pre-eklampsia – monimuotoinen tautikirjo. Kliin lab : kliinisen laboratorioalan julkaisu : SKKY:n jäsenlehti., 32(1), 7-9.

Publications in 2014

Raikkonen, K., O’Reilly, J. R., Pesonen, A-K., Kajantie, E., Villa, P., Laivuori, H., … Reynolds, R. M. (2014). Associations between maternal level of education and occupational status with placental glucocorticoid regeneration and sensitivity. Clinical Endocrinology, 81(2), 175-182. DOI:   http://dx.doi.org/10.1111/cen.12412

Keikkala, E., Ranta, J. K., Vuorela, P., Leinonen, R., Laivuori, H., Vaisanen, S., … Heinonen, S. (2014). Serum hyperglycosylated human chorionic gonadotrophin at 14-17 weeks of gestation does not predict preeclampsia. Prenatal Diagnosis, 34(7, SI), 699-705. DOI: http://dx.doi.org/10.1002/pd.4335

Kaartokallio, T., Klemetti, M. M., Timonen, A., Uotila, J., Heinonen, S., Kajantie, E., … Laivuori, H. (2014). Microsatellite Polymorphism in the Heme Oxygenase-1 Promoter Is Associated With Nonsevere and Late-Onset Preeclampsia. Hypertension, 64(1), 172-177. DOI: http://dx.doi.org/10.1161/HYPERTENSIONAHA.114.03337

Myatt, L., Redman, C. W., Staff, A. C., Hansson, S., Wilson, M. L., Laivuori, H., … Global Pregnancy CoLab COLAB (2014). Strategy for Standardization of Preeclampsia Research Study Design. Hypertension, 63(6), 1293-1301. DOI: http://dx.doi.org/10.1161/HYPERTENSIONAHA.114.03173

Kvehaugen, A. S., Melien, O., Holmen, O. L., Laivuori, H., Dechend, R., & Staff, A. C. (2014). Hypertension after preeclampsia and relation to the C1114G polymorphism (rs4606) in RGS2: data from the Norwegian HUNT2 study. BMC Medical Genetics, 15, [28]. 10.1186/1471-2350-15-28. DOI: http://dx.doi.org/10.1186/1471-2350-15-28

Villa, P. M., Kajantie, E., & Laivuori, H. (2014). Asetyylisalisyylihappo ja pre-eklampsian ehkäisy. Duodecim, 130(3), 243-250.

Lokki, I., Heikkinen-Eloranta, J., Jarva, H., Saisto, T., Lokki, M-L., Laivuori, H., & Meri, S. (2014). Complement activation and regulation in preeclamptic placenta. Frontiers in immunology, 5, 1-14. [312]. DOI: http://dx.doi.org/10.3389/fimmu.2014.00312

 

Publications in 2013

Keikkala E, Vuorela P, Laivuori H, Romppanen J, Heinonen S, Stenman U-H. First trimester hyperglycosylated human chorionic gonadotrophin in serum – A marker of early-onset preeclampsia. Placenta. 2013 Nov;34(11):1059-1065.

Miettola S, Hovi P, Andersson S, Strang-Karlsson S, Pouta A, Laivuori H et al. Maternal preeclampsia and bone mineral density of the adult offspring. American Journal of Obstetrics and Gynecology. 2013 Nov;209(5).

Majander KK, Villa PM, Kivinen K, Kere J, Laivuori H. A follow-up linkage study of Finnish pre-eclampsia families identifies a new fetal susceptibility locus on chromosome 18. European Journal of Human Genetics. 2013 Sep;21(9):1024-1026.

Klemetti MM, Teramo K, Nuutila M, Tikkanen M, Hiilesmaa V, Laivuori H. Blood pressure levels but not hypertensive complications have increased in Type1 diabetes pregnancies during 1989-2010. Diabetic Medicine. 2013 Sep;30(9):1087-1093.

Sandbacka M, Laivuori H, Freitas E, Halttunen M, Jokimaa V, Morin-Papunen L et al. TBX6, LHX1 and copy number variations in the complex genetics of Mullerian aplasia. Orphanet journal of rare diseases. 2013 Aug 16;8.

Johnson MP, Brennecke SP, East CE, Dyer TD, Roten LT, Proffitt JM et al. Genetic dissection of the pre-eclampsia susceptibility locus on chromosome 2q22 reveals shared novel risk factors for cardiovascular disease. Molecular Human Reproduction. 2013 Jul;19(7):423-437.

Villa PM, Hämäläinen E, Maki A, Räikkönen K, Pesonen A-K, Taipale P et al. Vasoactive agents for the prediction of early- and late-onset preeclampsia in a high-risk cohort. BMC Pregnancy and Childbirth. 2013 May 12;13.

Villa PM, Kajantie E, Räikkönen K, Pesonen A-K, Hämäläinen E, Vainio M et al. Aspirin in the prevention of pre-eclampsia in high-risk women. BJOG : An International Journal of Obstetrics & Gynaecology. 2013 May;120(6):773-773.

Kvehaugen AS, Melien O, Holmen OL, Laivuori H, Oian P, Andersgaard AB et al. Single Nucleotide Polymorphisms in G Protein Signaling Pathway Genes in Preeclampsia. Hypertension. 2013 Mar;61(3):655-+.

Villa PM, Kajantie E, Räikkönen K, Pesonen AK, Hämäläinen E, Vainio M et al. Aspirin in the prevention of pre-eclampsia in high-risk women: a randomised placebo-controlled PREDO Trial and a meta-analysis of randomised trials. BJOG : An International Journal of Obstetrics & Gynaecology. 2013 Jan;120(1):64-74.

Villa P, Laivuori H. Pre-eklampsia on monimuotoinen tautikirjo. Suomen lääkärilehti. 2013;68(43):2731.

Publications in 2012

Herse F, Lamarca B, Hubel CA, Kaartokallio T, Lokki AI, Ekholm E, Laivuori H, Gauster M, Huppertz B, Sugulle M, Ryan MJ, Novotny S, Brewer J, Park JK, Kacik M, Hoyer J, Verlohren S, Wallukat G, Rothe M, Luft FC, Muller DN, Schunck WH, Staff AC, Dechend R. CYP2J2 Expression and Circulating Epoxyeicosatrienoic Metabolites in Preeclampsia. Circulation. 2012 Nov 15.

Villa P, Kajantie E, Räikkönen K, Pesonen AK, Hämäläinen E, Vainio M, Taipale P, Laivuori H; on behalf of the PREDO Study group. Aspirin in the prevention of pre-eclampsia in high-risk women: a randomised placebo-controlled PREDO Trial and a meta-analysis of randomised trials. BJOG. 2012 Nov 6.

Roberge S, Giguère Y, Villa P, Nicolaides K, Vainio M, Forest JC, von Dadelzen P, Vaiman D, Tapp S, Bujold E. Early administration of low-dose aspirin for the prevention of severe and mild preeclampsia: a systematic review and meta-analysis. Am J Perinatol. 2012 Aug;29(7):551-6. Review.

Johnson MP, Brennecke SP, East CE, Göring HH, Kent JW Jr, Dyer TD, Said JM, Roten LT, Iversen AC, Abraham LJ, Heinonen S, Kajantie E, Kere J, Kivinen K, Pouta A, Laivuori H; FINNPEC Study Group, Austgulen R, Blangero J, Moses EK. Genome-wide association scan identifies a risk locus for preeclampsia on 2q14, near the inhibin, beta B gene. PLoS One. 2012;7(3)

Publications in 2011

Lokki AI, Klemetti MM, Heino S, Hiltunen L, Heinonen S, Laivuori H. Association of the rs1424954 polymorphism of the ACVR2A gene with the risk of pre-eclampsia is not replicated in a Finnish study population. BMC Res Notes. 2011 Dec 19;4:545.

Turunen R, Andersson S, Laivuori H, Kajantie E, Siitonen S, Repo H, Nupponen I. Increased postnatal inflammation in mechanically ventilated preterm infants born to mothers with early-onset preeclampsia. Neonatology. 2011;100(3):241-7.

Hiltunen LM, Laivuori H, Rautanen A, Kaaja R, Kere J, Krusius T, Rasi V, Paunio M. Factor V Leiden as a risk factor for preterm birth–a population-based nested case-control study. JThromb Haemost. 2011 Jan;9(1):71-8.

Publications in 2009

Villa PM, Laivuori H, Kajantie E, Kaaja R. Free fatty acid profiles in preeclampsia.Prostaglandins Leukot Essent Fatty Acids. 2009 Jul;81(1):17-21.

Peterson H, Laivuori H, Kerkelä E, Jiao H, Hiltunen L, Heino S, Tiala I, Knuutila S, Rasi V, Kere J, Kivinen K. ROCK2 allelic variants are not associated with pre-eclampsia susceptibility in the Finnish population. Mol Hum Reprod. 2009 Jul;15(7):443-9.

Hiltunen LM, Laivuori H, Rautanen A, Kaaja R, Kere J, Krusius T, Paunio M, Rasi V. Blood group AB and factor V Leiden as risk factors for pre-eclampsia: a population-based nested case-control study. Thromb Res. 2009 Jun;124(2):167-73.